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Quetiapine has been used to treat the loss of touch with reality (psychosis). Antihistamines or a topical steroid can be prescribed for management of pruritis. However, due to the heterogeneous effect of the trials, and with only a few studies showing substantial clinical response or remission, this statistical significance may not necessarily translate into a clinically relevant effect.[25] Try using an antidote (There are many possibilities: Amantadine, Bethanechol, Bupropion, Buspirone, Cyproheptadine, Dextroamphetamine, Methyphenidate, Mirtazapine, Nefazodone, Neostigmine, Yohimbine. The researchers do not know exactly why this occurred, but the thought is that they raise levels of serotonin and tryptophan. Give your body a chance to start unwinding before heading into bed for the night. You should notify your doctor if you experience persistent symptoms from lithium or if you develop diarrhea, vomiting, fever, unsteady walking, fainting, confusion, slurred speech, or rapid heart rate. Drug interactions: Anticonvulsants can interact with other drugs -- even aspirin -- to cause serious problems. Talk to your doctor if it continues. Like ENHANCE, five recent major clinical studies have failed to meet their primary endpoints.